1392812-51-9

Basic information

• Product Name: 2-(4-nitrobenzylidene)-1-(quinolin-4-yl)hydrazine
• CAS NO: 1392812-51-9
• Molecular Weight: 292.297
• Mol File: 1392812-51-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-nitrobenzylidene)-1-(quinolin-4-yl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrobenzylidene)-1-(quinolin-4-yl)hydrazine(1392812-51-9)
• EPA Substance Registry System: 2-(4-nitrobenzylidene)-1-(quinolin-4-yl)hydrazine(1392812-51-9)

Safety Data

• Hazardous Substances Data: 1392812-51-9(Hazardous Substances Data)

Upstream product

• 15793-93-8 4-hydrazineylquinoline 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1

Plasmodium falciparum subtilisin-like protease 1 (PfSUB1) is a serine protease that plays key roles in the egress of the parasite from red blood cells and in preparing the released merozoites for the subsequent invasion of new erythrocytes. The development of potent and selective PfSUB1 inhibitors could pave the way to the discovery of potential antimalarial drugs endowed with an innovative mode of action and consequently able to overcome the current problems of resistance to established chemotherapies. Through the screening of a proprietary library of compounds against PfSUB1, we identified hydrazone 2 as a hit compound. Here we report a preliminary investigation of the structure-activity relationships for a class of PfSUB1 inhibitors related to our identified hit.