139308-65-9 Usage
Uses
Used in Pharmaceutical Industry:
Tolafentrine is used as a therapeutic agent for the treatment of chronic experimental pulmonary hypertension. It works by inhibiting the activity of phosphodiesterase 3 and 4 enzymes, which play a role in the regulation of blood pressure and blood vessel constriction. By inhibiting these enzymes, Tolafentrine can help to improve blood flow and reduce the symptoms associated with pulmonary hypertension.
Check Digit Verification of cas no
The CAS Registry Mumber 139308-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,0 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 139308-65:
(8*1)+(7*3)+(6*9)+(5*3)+(4*0)+(3*8)+(2*6)+(1*5)=139
139 % 10 = 9
So 139308-65-9 is a valid CAS Registry Number.
InChI:InChI=1/C28H31N3O4S/c1-18-5-11-21(12-6-18)36(32,33)30-20-9-7-19(8-10-20)28-23-16-27(35-4)26(34-3)15-22(23)24-17-31(2)14-13-25(24)29-28/h5-12,15-16,24-25,30H,13-14,17H2,1-4H3/t24-,25-/m0/s1
139308-65-9Relevant academic research and scientific papers
Sulphonyl compound
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, (2008/06/13)
Compound of the formula I STR1 wherein the substituents have the meanings given in the description, are new active bronchodilators.
