1393092-85-7

Basic information

• Product Name: 2,4-di(m-tolyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
• Synonyms: 2,4-di(m-tolyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
• CAS NO: 1393092-85-7
• Molecular Weight: 328.457
• Mol File: 1393092-85-7.mol

Chemical Properties

• CAS DataBase Reference: 2,4-di(m-tolyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-di(m-tolyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine(1393092-85-7)
• EPA Substance Registry System: 2,4-di(m-tolyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine(1393092-85-7)

Safety Data

• Hazardous Substances Data: 1393092-85-7(Hazardous Substances Data)

Upstream product

• 95-54-5 1,2-diamino-benzene 
• 59826-44-7 1,3-di-(m-tolyl)propane-1,3-dione 
• 1393093-35-0 2,4-di(m-tolyl)-3H-1,5-benzodiazepine 

Relevant articles and documents

Dynamic Kinetic Resolution Approach for the Asymmetric Synthesis of Tetrahydrobenzodiazepines Using Transfer Hydrogenation by Chiral Phosphoric Acid

Asymmetric synthesis of tetrahydrobenzodiazepines was achieved by transfer hydrogenation of dihydrobenzodiazepines with benzothiazoline having a hydrogen-bonding donor substituent by means of a newly synthesized chiral phosphoric acid. This method was applicable to various racemic dihydrobenzodiazepines to give the corresponding products in good yields with excellent diastereoselectivities and enantioselectivities taking advantage of the dynamic kinetic resolution. Furthermore, the effect of bulky substituent at 3,3′-position on the catalyst and hydrogen-bonding donor substituent on benzothiazoline was fully elucidated by the theoretical study.

Asymmetric hydrogenation of 2,4-disubstituted 1,5-benzodiazepines using cationic ruthenium diamine catalysts: An unusual achiral counteranion induced reversal of enantioselectivity

BArFing it out the other way: A highly enantioselective hydrogenation of 2,4-disubstituted 1,5-benzodiazepines using chiral cationic ruthenium diamine catalysts (R,R)-1 has been developed (see scheme; BArF=tetrakis(3,5- bistrifluoromethylphenyl)borate). E