1393112-51-0

Basic information

• Product Name: (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate
• Synonyms: (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate
• CAS NO: 1393112-51-0
• Molecular Weight: 359.489
• Mol File: 1393112-51-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate(1393112-51-0)
• EPA Substance Registry System: (RS)-S-ethyl 2-(tert-butoxycarbonylamino)-3-(naphthalen-2-yl)propanethioate(1393112-51-0)

Safety Data

• Hazardous Substances Data: 1393112-51-0(Hazardous Substances Data)

Upstream product

• 56583-58-5 N-tert-butoxycarbonyl-3-(2-naphthyl)-L-alanine 

Downstream Products

• 56583-58-5 N-tert-butoxycarbonyl-3-(2-naphthyl)-L-alanine 

Relevant articles and documents

Naphthyl-l-α-amino acids via chemo-enzymatic dynamic kinetic resolution

A double catalyst system (protease + base) was applied to the dynamic kinetic resolution (DKR) of isomeric 1- and 2-α-naphthyl-glycines and -alanines exploiting the in situ racemization of their thioesters. Due to the different C-acidity of the two sets of compounds, different experimental conditions have been devised to perform the simultaneous resolution/racemization process. In all cases, the racemic N-Boc-thioesters were converted into the aminoacids with an l-configuration almost quantitatively and with complete enantioselectivity. 2012 Elsevier Ltd.