139331-42-3 Usage
General Description
2-(Chloromethyl)-2H-1,4-benzothiazin-3(4H)-one is a synthetic chemical compound with potential applications in pharmaceuticals and agrochemicals. It is a benzothiazine scaffold containing a chloromethyl group, and its structure allows for diverse chemical manipulations to create analogues with varying biological activities. 2-(CHLOROMETHYL)-2H-1,4-BENZOTHIAZIN-3(4H)-ONE is of interest in medicinal chemistry due to its potential as a starting point for the development of new drugs, particularly in the area of antimicrobial and antitubercular agents. Additionally, its reactivity and potential for modification make it a valuable building block for the synthesis of novel molecules in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 139331-42-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,3,3 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 139331-42:
(8*1)+(7*3)+(6*9)+(5*3)+(4*3)+(3*1)+(2*4)+(1*2)=123
123 % 10 = 3
So 139331-42-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H8ClNOS/c10-5-8-9(12)11-6-3-1-2-4-7(6)13-8/h1-4,8H,5H2,(H,11,12)
139331-42-3Relevant articles and documents
Synthesis and biological activities of new 1,4-benzothiazine derivatives
Kajino,Mizuno,Tawada,Shibouta,Nishikawa,Meguro
, p. 2888 - 2895 (2007/10/02)
New 2H-1,4-benzothiazin-3(4H)-one derivatives possessing (4-phenyl-1-piperazinyl)alkyl moieties at the 2-position were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities. Antihypertensive effects in spontaneously hypertensive rats were also evaluated. In general, these compounds were rather weak calcium channel blockers, although, in contrast, many of them had moderate to potent calmodulin antagonistic activity, and 2-[3-(4-(4-fluorophenyl)-1-piperazinyl]propyl]-2H-1,4-benzothiazin-3(4H )-one derivatives 45, 74 and 75 showed potent antihypertensive effects.
