1393345-07-7Relevant academic research and scientific papers
Catalytic asymmetric Mannich-type reactions of α-cyano α-sulfonyl carbanions
Ohmatsu, Kohsuke,Goto, Ayano,Ooi, Takashi
scheme or table, p. 7913 - 7915 (2012/09/22)
An efficient asymmetric Mannich-type reaction of α-cyano α-sulfonyl carbanions has been achieved by exploiting the structural modularity and anion-recognition ability of chiral 1,2,3-triazolium ions. This protocol has proven to be applicable to a variety of N-Boc imines and cyanosulfones, affording β-amino α-cyanosulfones in excellent yields with high stereoselectivities.
