1393366-08-9

Basic information

• Product Name: C₂₀H₁₇NO₂
• Synonyms: C₂₀H₁₇NO₂
• CAS NO: 1393366-08-9
• Molecular Weight: 303.36
• Mol File: 1393366-08-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₇NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₇NO₂(1393366-08-9)
• EPA Substance Registry System: C₂₀H₁₇NO₂(1393366-08-9)

Safety Data

• Hazardous Substances Data: 1393366-08-9(Hazardous Substances Data)

Upstream product

• 28737-29-3 1‐ethylindole‐2‐carboxylic acid 
• 2327-99-3 1-phenylpropadiene 

Relevant articles and documents

Palladium-catalyzed annulation of allenes with indole-2-carboxylic acid derivatives: Synthesis of Indolo[2,3-c]pyrane-1-ones via Ar-I Reactivity or C-H functionalization

Two methodologies, one involving Ar-I reactivity and the other through C-H functionalization, for the formation of indolo[2,3-c]pyrane-1-ones via the corresponding allenes, are presented. A highly efficient approach to indolo[2,3-c]pyrane-1-one derivatives through the Pd-catalyzed regioselective annulation of allenes with 3-iodo-1-alkylindole-2-carboxylic acids is described. This method is fairly general for a wide range of allenes affording the respective indolo[2,3-c]pyrane-1-ones in good to excellent yields. In addition, a Pd(II)-catalyzed oxidative coupling of indole-2-caboxylic acid derivatives with allenes via direct C-H functionalization to afford the corresponding indolo[2,3-c]pyrane-1-ones in moderate to good yields has been developed.