139338-95-7Relevant academic research and scientific papers
Total synthesis of the rubrolone aglycon
Boger,Ichikawa,Jiang
, p. 12169 - 12173 (2000)
A total synthesis of the rubrolone aglycon is detailed and is based on two key Diels-Alder reactions. The AB ring system incorporating a tetrasubstituted pyridine was assembled, enlisting the rare 4π participation of an O-alkyl α,β-unsaturated oxime in an
Studies on the synthesis of rubrolone: 4π Participation of O-alkyl α,β-unsaturated oximes in intramolecular [4 + 2] cycloaddition reactions
Boger,Zhu
, p. 7643 - 7646 (2007/10/02)
The effective 4π participation of O-alkyl α,β-unsaturated oximes, 1-aza-1,3-butadienes, in intramolecular Diels-Alder reactions is described in studies on the synthesis of the rubrolone AB ring system.
