1393478-29-9Relevant articles and documents
A chiron approach to aminocytitols by petasis-borono-mannich reaction: Formal synthesis of (+)-conduramine e and (-)-conduramine e
Ghosal, Partha,Shaw, Arun K.
, p. 7627 - 7632,6 (2012)
A chiron approach to a stereoselective route for the synthesis of aminocytitols from carbohydrates is described. The formal synthesis of (+)-conduramine E and (-)-conduramine E was achieved by utilizing this strategy. The key features of the synthetic strategy include one-pot three-component Petasis-Borono-Mannich reaction to introduce the syn-β-amino alcohol functionality of conduramine E and ring-closing metathesis to construct its carbocyclic core. The present synthetic approach paves the way for stereoselective synthesis of several conduramines starting from carbohydrates.