1393533-91-9Relevant academic research and scientific papers
Lewis acid-triggered selective zincation of chromones, quinolones, and thiochromones: Application to the preparation of natural flavones and isoflavones
Klier, Lydia,Bresser, Tomke,Nigst, Tobias A.,Karaghiosoff, Konstantin,Knochel, Paul
, p. 13584 - 13587 (2012)
A Lewis acid-triggered zincation allows the regioselective metalation of various chromones and quinolones. In the absence of MgCl2, a C(3) zincation is observed, whereas in the presence of MgCl2 or a related Lewis acid, C(2) zincation occurs. Applications to a natural flavone, isoflavone, and quinolone are shown.
