139367-69-4

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 151332-00-2 2-formyl-3-(3-chlorophenyl)pentanedinitrile 
• 151332-03-5 1-ethyl 2-methyl 3-amino-4-<2-cyano-1-(3-chlorophenyl)ethyl>-1H-pyrrole-1,2-dicarboxylate 
• 151332-01-3 methyl N-<2,4-dicyano-3-(3-chlorophenyl)-1-butenyl>glycine 
• 135851-20-6 3-(3-chlorophenyl)pentanedinitrile 
• 151332-09-1 N-benzoyl-N'-<4-<2-cyano-1-(3-chlorophenyl)ethyl>-2-(methoxycarbonyl)-1H-pyrrol-3-yl>-S-methylthiourea 
• 151332-07-9 N-benzoyl-N'-<4-<2-cyano-1-(3-chlorophenyl)ethyl>-2-(methoxycarbonyl)-1H-pyrrol-3-yl>thiourea 
• 151332-05-7 methyl 3-amino-4-<2-cyano-1-(3-chlorophenyl)ethyl>-1H-pyrrole-2-carboxylate 

Downstream Products

• 151332-16-0 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(3-chlorophenyl)-N-(phenylethyl)propanamide 
• 151332-17-1 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(3-chlorophenyl)-N-(phenylethyl)propanamide 
• 151433-90-8 3-(2-amino-4-oxo-3H,5H-pyrrolo<3,2-d>pyrimidin-7-yl)-3-(3-chlorophenyl)propanoic acid 

Relevant academic research and scientific papers

Structure-Based Design of Inhibitors of Purine Nucleoside Phosphorylase. 3. 9-Arylmethyl Derivatives of 9-Deazaguanine Substituted on the Methylene Group

X-ray crystallography and computer-assisted molecular modeling (CAMM) studies aided in the design of a potent series of Mammalian purine nucleoside phosphorylase (PNP) inhibitors.Enhanced potency was achieved by designing substituted 9-(arylmethyl)-9-deaz