1393672-12-2Relevant academic research and scientific papers
Deactivation of gold(i) catalysts in the presence of thiols and amines-characterisation and catalysis
Young, Paul C.,Green, Samantha L. J.,Rosair, Georgina M.,Lee, Ai-Lan
, p. 9645 - 9653 (2013/08/23)
Thiols and amines, which are common heteroatom nucleophiles in gold-catalysed reactions, are known to dampen the reactivity of gold catalysts. In this article, the identity and activity of gold(i) catalysts in the presence of thiols and amines is investig
Gold(I)-catalyzed addition of thiols and thioacids to 3,3-disubstituted cyclopropenes
Mudd, Richard J.,Young, Paul C.,Jordan-Hore, James A.,Rosair, Georgina M.,Lee, Ai-Lan
, p. 7633 - 7639 (2012/10/29)
Gold(I)-catalyzed reactions of thiols, thiophenols, and thioacids with 3,3-disubstituted cyclopropenes occur in a regioselective and chemoselective manner to produce either vinyl thioethers or primary allylic thioesters in good yields. A survey of commonly used gold(I) catalysts shows Echavarren's cationic gold(I) catalyst to be most tolerant of deactivation by sulfur. A novel digold with bridging thiolate complex is characterized by X-ray crystallography, shedding light on a possible deactivation pathway.
