1393682-18-2

Basic information

• Product Name: (1S,5S,6R,7R)-7-chloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one
• Synonyms: (1S,5S,6R,7R)-7-chloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one
• CAS NO: 1393682-18-2
• Molecular Weight: 309.793
• Mol File: 1393682-18-2.mol

Chemical Properties

• CAS DataBase Reference: (1S,5S,6R,7R)-7-chloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,5S,6R,7R)-7-chloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one(1393682-18-2)
• EPA Substance Registry System: (1S,5S,6R,7R)-7-chloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one(1393682-18-2)

Safety Data

• Hazardous Substances Data: 1393682-18-2(Hazardous Substances Data)

Upstream product

• 1393682-13-7 (1S,5S,6R)-7,7-dichloro-2-(2,4-dimethoxybenzyl)-5-methyl-2-azabicyclo[4.1.0]heptan-3-one 

Relevant articles and documents

New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714

In an experimental permanent stroke model, we report here the contribution of ONO-1714 to brain damage prevention. Daily drug administration, twenty-one days prior to and two days after an experimental infarct, was performed by using mini-osmotic pumps (ALZET). Infarct volumes were assessed by image analysis of sequential coronal brain 1 mm3 sections stained following the 2,3,5-triphenyltetrazolium chloride histological staining technique. Results of this study provide evidence of a significant reduction of the brain lesion size, suggesting ONO-1714 as a potential neuroprotective agent in stroke patients. ONO-1714 was prepared in our laboratory following a procedure which resulted in the supply of the desired compound in an easy and excellent yield.