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1393712-18-9

PF-05139962 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1393712-18-9 Structure

  • Basic information

    1. Product Name: PF-05139962
    2. Synonyms: PF-05139962
    3. CAS NO:1393712-18-9
    4. Molecular Formula: C21H27N5O4S
    5. Molecular Weight: 445.542
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1393712-18-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: PF-05139962(CAS DataBase Reference)
    10. NIST Chemistry Reference: PF-05139962(1393712-18-9)
    11. EPA Substance Registry System: PF-05139962(1393712-18-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1393712-18-9(Hazardous Substances Data)

1393712-18-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1393712-18-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,3,7,1 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1393712-18:
(9*1)+(8*3)+(7*9)+(6*3)+(5*7)+(4*1)+(3*2)+(2*1)+(1*8)=169
169 % 10 = 9
So 1393712-18-9 is a valid CAS Registry Number.

1393712-18-9Downstream Products

1393712-18-9Relevant articles and documents

Conformationally-restricted cyclic sulfones as potent and selective mTOR kinase inhibitors

Liu, Kevin K.-C.,Bailey, Simon,Dinh, Dac M.,Lam, Hieu,Li, Chunze,Wells, Peter A.,Yin, Min-Jean,Zou, Aihua

, p. 5114 - 5117 (2012)

Novel conformationally-restricted mTOR kinase inhibitors with cyclic sulfone scaffold were designed. Synthesis and structure-activity relationship (SAR) studies are described with emphasis on optimization of the mTOR potency and selectivity against class I PI3Kα kinase. PF-05139962 was identified with excellent mTOR biochemical inhibition, cellular potency, kinase selectivity and in vitro ADME properties.

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