1393722-83-2

Upstream product

• 485-72-3 7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on 
• 908104-37-0 7-hydroxy-3-(4-methoxy-3-nitrophenyl)-4H-chromen-4-one 
• 75-21-8 oxirane 
• 1393722-68-3 7-(2-methylallyloxy)-3-(3-amino-4-methoxyphenyl)-4H-chromen-4-one 

Downstream Products

• 1393723-01-7 7-(2-methylallyloxy)-3-(3-(bis(2-chloroethyl)amino)-4-methoxyphenyl)-4H-chromen-4-one 

Relevant academic research and scientific papers

Synthesis and antitumor activity of formononetin nitrogen mustard derivatives

A series of formononetin nitrogen mustard derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (SH-SY5Y, HCT-116, DU-145, Hela and SGC-7901). The pharmacological results showed that many of the new derivatives displayed more potent cytotoxicity than alkeran. Furthermore, compounds 6d and 6n could induce cell cycle arrest at G2/M phase and cell apoptosis.