1393803-25-2

Upstream product

• 1393803-23-0 (4R,5S)-1-(4-methoxybenzyl)-4-benzyloxy-5-[2-(methyloxycarbonyl)ethyl]pyrrolidin-2-one 
• 622833-72-1 (R)-1-(4-methoxybenzyl)-3-(benzyloxy)pyrrolidine-2,5-dione 

Downstream Products

• 1393803-53-6 C₄₀H₃₉F₆NO₆ 
• 1393803-36-5 C₄₀H₃₉F₆NO₆ 
• 1393803-27-4 (4R,5S,8R)-1-(4-methoxybenzyl)-4-benzyloxy-5-[3-benzyloxy-4-(3-(trifluoromethyl)phenyl)butyl]pyrrolidin-2-one 
• 1393803-28-5 (4R,5S,8R)-4-benzyloxy-5-[3-benzyloxy-4-(3-(trifluoromethyl)phenyl)butyl]pyrrolidin-2-one 
• 1393803-29-6 iso-propyl (4R,5S,8R)-5-(3-(3-benzyloxy-2-(3-benzyloxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)propyl)-thiophene-2-carboxylate 
• 1393803-30-9 iso-propyl (4R,5S,8R)-5-(3-(3-hydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)propyl)-thiophene-2-carboxylate 
• 1393803-32-1 methyl (4R,5S,8R)-7-(3-benzyloxy-2-(3-benzyloxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoate 
• 1393803-33-2 methyl (4R,5S,8R)-7-(3-hydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoate 
• 1393803-34-3 (4R,5S,8R)-7-(3-hydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoic acid 
• 1393803-35-4 (4R,5S,8R)-1-(4-methoxybenzyl)-4-hydroxy-5-[3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl]pyrrolidin-2-one 
• 1393803-26-3 (4R,5S,8R)-1-(4-methoxybenzyl)-4-benzyloxy-5-[3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl]pyrrolidin-2-one 
• 1393803-52-5 (4R,5S,8S)-1-(4-methoxybenzyl)-4-benzyloxy-5-[3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl]pyrrolidin-2-one 

Relevant academic research and scientific papers

SmI2-Mediated intermolecular coupling of γ-lactam N-α-radicals with activated alkenes: Asymmetric synthesis of 11-hydroxylated analogues of the lead compounds CP-734432 and PF-04475270

We report, for the first time, the synthesis of 8-aza-analogues of PGE 2. The SmI2-mediated cross coupling reactions of γ-lactam-hemiaminal 9, lactam 2-pyridyl sulfide 17, and lactam 2-pyridyl sulfone 18 with activated alkenes/alkyne