1393810-65-5

Basic information

• Product Name: N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide
• Synonyms: N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide
• CAS NO: 1393810-65-5
• Molecular Weight: 738.702
• Mol File: 1393810-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide(1393810-65-5)
• EPA Substance Registry System: N-(((2S,3R,4R)-1-allyl-3-(2-bromophenyl)-4-((trityloxy)methyl)azetidin-2-yl)methyl)-2-nitrobenzenesulfonamide(1393810-65-5)

Safety Data

• Hazardous Substances Data: 1393810-65-5(Hazardous Substances Data)

Upstream product

• 76-83-5 trityl chloride 
• 1393810-64-4 C₃₃H₃₃BrN₂O 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 1393810-56-4 (2S,3R,4R)-1-allyl-3-(2-bromophenyl)-2-((trityloxy)methyl)azetidine-4-carbonitrile 
• 1393810-52-0 C₁₂H₁₆BrNO₂ 

Downstream Products

• 1393810-69-9 ((1S,2aR,8bR)-2-allyl-4-((2-nitrophenyl )sulfonyl)-1,2,2a,3,4,8b-hexahydroazeto[2,3-c]quinolin-1-yl)methanol 
• 1393810-67-7 (1S,2aR,8bR)-2-allyl-4-((2-nitrophenyl)sulfonyl)-1-((trityloxy)methyl)-1,2,2a,3,4,8b-hexahydroazeto[2,3-c]quinolone 

Relevant articles and documents

Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries

The synthesis and diversification of a densely functionalized azetidine ring system to gain access to a wide variety of fused, bridged, and spirocyclic ring systems is described. The in vitro physicochemical and pharmacokinetic properties of representative library members are measured in order to evaluate the use of these scaffolds for the generation of lead-like molecules to be used in targeting the central nervous system. The solid-phase synthesis of a 1976-membered library of spirocyclic azetidines is also described.