1393880-53-9Relevant academic research and scientific papers
Stereoselective preparation of β-aryl-β-boronyl enoates and their copper-catalyzed enantioselective conjugate reduction
Ding, Jinyue,Lee, Jack Chang Hung,Hall, Dennis G.
supporting information, p. 4462 - 4465 (2012/10/30)
A new methodology has been developed for the stereoselective preparation of β-aryl-β-boronyl α,β-unsaturated esters via Heck coupling, and their subsequent copper(I)-catalyzed enantioselective conjugate reduction. Various chiral secondary boronate derivatives can be accessed in excellent yields and good to high levels of enantioselectivity through the efficient copper-catalyzed process using polymethylhydrosiloxane (PMHS) as the hydride source.
