1393882-97-7Relevant academic research and scientific papers
An alternative strategy to the Pictet-Spengler method for tetrahydroisoquinoline synthesis: A feasibility study
Henderson, Laura,Knight, David W.,Williams, Andrew C.
scheme or table, p. 4657 - 4660 (2012/09/05)
Acid-catalysed cyclisations of the 2-aminoethyl styrene derivatives 9 give good to excellent yields of the corresponding tetrahydroisoquinolines 7 by an intramolecular hydroamination reaction, which represents an alternative and potentially more flexible strategy to the classical Pictet-Spengler method for the syntheses of such heterocycles.
