1394017-31-2

Basic information

• Product Name: 5-chloro-N-(1-(4-cyanophenyl)-3-methyl-1-oxobutan-2-yl)-2-fluorobenzamide
• Synonyms: 5-chloro-N-(1-(4-cyanophenyl)-3-methyl-1-oxobutan-2-yl)-2-fluorobenzamide
• CAS NO: 1394017-31-2
• Molecular Weight: 358.8
• Mol File: 1394017-31-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-chloro-N-(1-(4-cyanophenyl)-3-methyl-1-oxobutan-2-yl)-2-fluorobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-N-(1-(4-cyanophenyl)-3-methyl-1-oxobutan-2-yl)-2-fluorobenzamide(1394017-31-2)
• EPA Substance Registry System: 5-chloro-N-(1-(4-cyanophenyl)-3-methyl-1-oxobutan-2-yl)-2-fluorobenzamide(1394017-31-2)

Safety Data

• Hazardous Substances Data: 1394017-31-2(Hazardous Substances Data)

Upstream product

• 1394017-92-5 4-(2-amino-3-methylbutanoyl)benzonitrile hydrochloride 
• 394-30-9 5-chloro-2-fluorobenzoic acid 

Relevant articles and documents

N-1-Alkyl-2-oxo-2-aryl amides as novel antagonists of the TRPA1 receptor

A series of potent antagonists of the ion channel transient receptor potential A1 (TRPA1) was developed by modifying lead structure 16 that was discovered by high-throughput screening. Based on lead compound 16, a SAR was established, showing a narrow region at the nitro-aromatic R1 moiety and at the warhead, while the R2 side had a much wider scope including ureas and carbamates. Compound 16 inhibits Ca2+-activated TRPA1 currents reversibly in whole cell patch clamp experiments, indicating that under in vivo conditions, it does not react covalently, despite its potentially electrophilic ketone.