1394137-75-7Relevant academic research and scientific papers
A practical entry to β-aryl-β-alkyl amino alcohols: Application to the synthesis of a potent BACE1 inhibitor
Delgado, Oscar,Monteagudo, Antonio,Van Gool, Michiel,Trabanco, Andrés A.,Fustero, Santos
, p. 6758 - 6766 (2012/09/22)
The 1,2-addition of alkyl Grignard reagents to readily available N-tert-butanesulfinyl ketimines, bearing an α-silyloxy substituent, proceeds in high yields and excellent diastereocontrol. The utility of the present method was demonstrated by the synthesi
