1394233-03-4Relevant academic research and scientific papers
Electrophilic ipso-iodocyclization of N-benzyl-N-(1-naphthyl)propiolamides: Synthesis of complex polycyclic lactams
Wang, Li-Jing,Zhu, Hai-Tao,Qiu, Yi-Feng,Liu, Xue-Yuan,Liang, Yong-Min
, p. 643 - 650 (2014/01/06)
An intramolecular electrophilic ipso-iodocyclization of N-benzyl-N-(1-naphthyl)propiolamides combined with the Friedel-Crafts-type reaction for the synthesis of complex polycyclic lactams is reported. The resulting iodinated cyclization product can provide a very useful handle for further structural manipulation. The Royal Society of Chemistry.
Dearomatization of fused arenes using platinum-catalyzed intramolecular formation of two C-C bonds
Shibuya, Tetsuro,Noguchi, Keiichi,Tanaka, Ken
, p. 6219 - 6222 (2012/07/17)
The (de)aroma of success: A cationic platinum(II) complex generated in situ catalyzes dearomatization of fused arenes by forming two intramolecular C-C bonds (see scheme). Mechanistic studies reveal that this reaction could proceed through alkyne activation by the cationic platinum(II) complex followed by a Friedel-Crafts-type reaction. Copyright
