1394252-85-7Relevant articles and documents
Mechanism of the regio- and diastereoselective ring expansion reaction using trimethylsilyldiazomethane
Sakai, Takeo,Ito, Satoshi,Furuta, Hiroki,Kawahara, Yuki,Mori, Yuji
, p. 4564 - 4567 (2012)
An equatorial attack of TMS-diazomethane was determined to be the first step of the BF3-promoted ring expansion reaction of six-membered ketones using TMS-diazomethane. The migration reaction occurred in a conformation in which the carbonyl oxygen and the TMS group were antiperiplanar to predominantly afford trans-seven-membered ketones.