1394253-37-2Relevant academic research and scientific papers
Bifunctional cinchona alkaloid/thiourea catalyzes direct and enantioselective vinylogous Michael addition of 3-alkylidene oxindoles to nitroolefins
Curti, Claudio,Rassu, Gloria,Zambrano, Vincenzo,Pinna, Luigi,Pelosi, Giorgio,Sartori, Andrea,Battistini, Lucia,Zanardi, Franca,Casiraghi, Giovanni
supporting information; experimental part, p. 6200 - 6204 (2012/08/07)
Vinylogy: Advances in asymmetric catalysis using the bifunctional cinchona alkaloid/thioureas enabled an umpolung of the classical Cβ reactivity of 3-alkylidene oxindoles, thus allowing the development of the first and sole example of a direct, organocatalytic asymmetric vinylogous Michael (AVM) reaction with nitroolefins. Copyright
