1394290-79-9Relevant academic research and scientific papers
A facile parallel synthesis of trifluoroethyl-substituted alkynes
Liu, Cui-Bo,Meng, Wei,Li, Feng,Wang, Shuai,Nie, Jing,Ma, Jun-An
, p. 6227 - 6230 (2012)
Trifluoroethylation made easy: The ease of execution of the reaction (see scheme), which runs under mild conditions and without the need for additional base or ligands, allows for the rapid parallel synthesis of a broad variety of trifluoroethylated alkynes. Both experimental and theoretical analyses indicate that the trifluoromethylcarbene could undergo concerted insertion into the Csp-H bond of the alkyne. Copyright
