139436-64-9

Basic information

• Product Name: Quinoxaline, 6-chloro-2-(4-methylphenyl)-
• CAS NO: 139436-64-9
• Molecular Formula: C15H11ClN2
• Molecular Weight: 254.719
• Mol File: 139436-64-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Quinoxaline, 6-chloro-2-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoxaline, 6-chloro-2-(4-methylphenyl)-(139436-64-9)
• EPA Substance Registry System: Quinoxaline, 6-chloro-2-(4-methylphenyl)-(139436-64-9)

Safety Data

• Hazardous Substances Data: 139436-64-9(Hazardous Substances Data)

Upstream product

• 95-83-0 4-Chloro-1,2-phenylenediamine 
• 619-41-0 4-(bromoacetyl)toluene 
• 18671-97-1 2,6-dichloroquinoxaline 
• 5720-05-8 4-methylphenylboronic acid 
• 17263-64-8 2-diazo-1-(4-methylphenyl)ethanone 
• 874-60-2 4-methyl-benzoyl chloride 
• 25755-82-2 3-(4-methylphenyl)isoxazol-5(4H)-one 

Downstream Products

• 1391118-59-4 6-(2-methoxyphenyl)-2-(p-tolyl)quinoxaline 
• 1391118-57-2 6-(4-tert-butylphenyl)-2-(p-tolyl)quinoxaline 
• 1391118-55-0 6-(3,5-dimethylphenyl)-2-(p-tolyl)quinoxaline 

Relevant articles and documents

A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclisation of 1,2-diamines and phenacyl bromides

A simple, efficient and eco-friendly method has been developed for quinoxaline synthesis from inexpensive and readily available diamines and phenacyl bromides by catalyst- and additive-free protocol.

Safe and reliable synthesis of diazoketones and quinoxalines in a continuous flow reactor

A flow method for the synthesis of aliphatic and aromatic diazoketones from acyl chloride precursors has been developed and used to prepare quinoxalines in a multistep sequence without isolation of the potentially explosive diazoketone. The protocol showcases an efficient in-line purification using supported scavengers with time-saving and safety benefits and in particular a reduction in the operator's exposure to carcinogenic phenylenediamines.