1394369-61-9Relevant articles and documents
Biomimetic synthesis of Cbz-(S)-dolaphenine
García-Reynaga, Pablo,Vannieuwenhze, Michael S.
supporting information, p. 4989 - 4993 (2012/11/07)
A new route to Cbz-(S)-dolaphenine, a recurring element in bioactive peptidic natural products, has been implemented, which closely parallels the biogenetic pathway. Cyclodehydration of 11 to yield thiazoline 2 allows for a Ni(0)-promoted decarbonylative aromatization to provide the thiazole framework with retention of stereochemistry.