139437-49-3

Basic information

• Product Name: Benzeneethanol, b-[(3-thienylmethylene)amino]-, (R)-
• CAS NO: 139437-49-3
• Molecular Formula: C13H13NOS
• Molecular Weight: 231.318
• Mol File: 139437-49-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneethanol, b-[(3-thienylmethylene)amino]-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanol, b-[(3-thienylmethylene)amino]-, (R)-(139437-49-3)
• EPA Substance Registry System: Benzeneethanol, b-[(3-thienylmethylene)amino]-, (R)-(139437-49-3)

Safety Data

• Hazardous Substances Data: 139437-49-3(Hazardous Substances Data)

Upstream product

• 498-62-4 3-thiophene carboxaldehyde 
• 56613-80-0 D-2-phenylglycinol 

Downstream Products

• 139437-65-3 (R)-2-[Methyl-((R)-1-thiophen-3-yl-ethyl)-amino]-2-phenyl-ethanol 
• 139437-69-7 (R)-2-[Methyl-((S)-1-thiophen-3-yl-ethyl)-amino]-2-phenyl-ethanol 
• 139437-61-9 (R)-2-Phenyl-2-((R)-1-thiophen-3-yl-ethylamino)-ethanol 

Relevant articles and documents

Chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams from ethylbromodifluoroacetate and imines during Reformatsky reaction

The chemoselective and stereoselective synthesis of gem-difluoro-β-aminoesters or gem-difluoro-β-lactams was investigated from ethylbromodifluoroacetate and imines during Reformatsky reaction. Influence of various reaction parameters, such as nature of the amine part, nature of the chiral auxiliary, was evaluated. High levels of stereoselectivity (up to 98%) were obtained for gem-difluoro-β-aminoesters and gem-difluoro-β-lactams using either (R)-phenylglycinol or (R)-methoxyphenylglycinol.