139448-95-6Relevant articles and documents
Site-Specific Incorporation of Multiple Thioamide Substitutions into a Peptide Backbone via Solid Phase Peptide Synthesis
Yang, Jinhua,Wang, Changliu,Yao, Chaochao,Chen, Chunqiu,Hu, Yafang,He, Guifeng,Zhao, Junfeng
, p. 1484 - 1494 (2020/01/02)
Among various peptide modification strategies, thioamide substitution by replacing the carbonyl oxygen atom of an amide bond with a sulfur atom constitutes an invaluable tool for chemical biology, for use in peptide drug discovery and protein structure-fu
Preparation and reactions of N-thioformyl peptides from amino thioacids and isonitriles
Yuan, Yu,Zhu, Jianglong,Li, Xuechen,Wu, Xiangyang,Danishefsky, Samuel J.
supporting information; experimental part, p. 2329 - 2333 (2009/09/06)
The preparation of N-thioformyl peptides from amino thioacids and isonitriles at room temperature is described.