139449-23-3

Upstream product

• 1776-09-6 3-bromochroman-4-one 
• 108-98-5 thiophenol 
• 2491-36-3 2-(2-bromoacetyl)hydroxybenzene 
• 118-93-4 o-hydroxyacetophenone 
• 67-68-5 dimethyl sulfoxide 
• 139449-21-1 3-phenylthio-2,3-dihydro-(4H)-benzopyran-4-one 

Downstream Products

• 491-37-2 2,3-dihydro-4H-1-benzopyran-4-one 
• 139449-39-1 3-cinnamyl-chroman-4-one 
• 97904-75-1 isoflavanone 
• 574-12-9 isoflavone 
• 139449-29-9 3-methyl-3-(phenylsulfonyl)chroman-4-one 
• 139449-30-2 3-phenylsulfonyl-3-(2-propenyl)chroman-4-one 
• 140870-46-8 3-phenyl-3-(phenylsulfonyl)chroman-4-one 
• 139449-31-3 3-Benzenesulfonyl-3-((E)-3-phenyl-allyl)-chroman-4-one 

Relevant academic research and scientific papers

MeONH 2·hCl-Mediated α-Methylenation/Conjugate Addition of α-Sulfonylo-Hydroxyacetophenones with Methyl Sulfoxides: Route to 3-Sulfonylchroman-4-ones

A novel and efficient route for the synthesis of 3-sulfonylchroman-4-ones from α-sulfonyl o -hydroxyacetophenones with methyl sulfoxides via a MeONH 2·HCl-mediated sequential methylenation/ conjugate addition is described. Plausible reaction mechanisms are proposed and discussed. Various reaction conditions for this novel, one-pot, environmentally friendly conversion were investigated.

Aryllead Triacetates as Synthons for the Synthesis of Biflavonoids. Part 2. Synthesis of Garcinia-Type Biflavonoid

Arylation of 3-(phenylsulfonyl)chroman-4-one 1 with simple aryllead triacetates affords the corresponding 3-aryl-3-(phenylsulfonyl)chroman-4-one in 64-74percent yield.However, no reaction took place with the hindered 2,4,6-trimethoxyphenyllead triacetate

Ligand Coupling Route to Isoflavanones and Isoflavones

Phenylation of 3-phenylsulfonylchroman-4-ones using Ph3BiCO3 leading to the synthesis of isoflavanones and isoflavones is reported.

A Facile Synthesis of 3-Alkylchromanones and Chromones

A simple and high yielding route to 3-alkylchromanones and 3-alkylchromones has been achieved from 3-alkyl-3-phenylsulphonyl-4-chromanones.