139470-88-5Relevant academic research and scientific papers
Kinetic Resolution of Chiral Hydroperoxides via Sharpless Epoxidation
Hoeft, E.,Hamann, H.-J.,Kunath, A.
, p. 534 - 537 (1994)
The kinetic resolution of tertiary hydroperoxides via catalytic Sharpless epoxidation with various allylic alcohols has been investigated.By using 1-cyclohexyl-1-phenylethyl hydroperoxide an enantiomeric excess (e.e.) of up to 29percent of the resolved hy
Kinetic resolution of hydroperoxides with enantiopure phosphines: Preparation of enantioenriched tertiary hydroperoxides
Driver, Tom G.,Harris, Jason R.,Woerpel
, p. 3836 - 3837 (2008/02/13)
An efficient reductive kinetic resolution strategy capable of accessing optically active tertiary hydroperoxides is reported. Readily accessible tertiary hydroperoxides are resolved with commercially available (R)- or (S)-xylyl-PHANEPHOS with selectivity factors as large as 37. The resulting bis(phosphine oxide) can be recycled in high yields. The isolated mono(phosphine oxide) intermediate resolved hydroperoxides with the same selectivity as the parent bisphosphine. Copyright
