1394816-76-2Relevant academic research and scientific papers
Ru(II)-Pheox catalyzed N-H insertion reaction of diazoacetamides: Synthesis of N-substituted α-aminoamides
Chanthamath, Soda,Thongjareun, Songkharm,Shibatomi, Kazutaka,Iwasa, Seiji
, p. 4862 - 4865 (2012/09/08)
An efficient protocol for the preparation of α-aminoamides was developed via the Ru(II)-dm-Pheox catalyzed N-H insertion reaction of various diazoacetamides with several amines, including aniline. This catalytic N-H insertion reaction was also applied to the synthesis of 2-(2-methylquinolin-4- ylamino)-N-phenylacetamide, a potential antileishmanial agent.
