139482-67-0Relevant academic research and scientific papers
New Bronchodilators. 3. Imidazonaphthyridin-4(5H)-ones
Suzuki, Fumio,Kuroda, Takeshi,Kawakita, Takashi,Manabe, Haruhiko,Kitamura, Shigeto,et al.
, p. 4866 - 4874 (2007/10/02)
In order to develop new oral bronchodilators, a series of novel imidazonaphthyridin-4(5H)-ones 5 were designed and synthesized.Some of these new heterocycles exhibited more potent bronchodilator activity in vitro and in vivo than theophylline.
New Antiinflammatory Agents. 2. 5-Phenyl-3H-imidazonaphthyridin-4(5H)-ones: A New Class of Nonsteroidal Antiinflammatory Agents with Potent Activity Like Glucocorticoids
Suzuki, Fumio,Kuroda, Takeshi,Tamura, Tadafumi,Sato, Soichiro,Ohmori, Kenji,Ichikawa, Shunji
, p. 2863 - 2870 (2007/10/02)
We previously described new antiinflammatory agents, 4-hydroxy-2-oxo-1-phenyl-1H-1,8-naphthyridine-3-carboxamides 1.Further modification of the compounds bearing 1-phenyl-1,8-naphthyridin-2-one as a mother skeleton led to 5-phenylimidazonaphth
