1394824-31-7Relevant articles and documents
Metal-free N-H insertions of donor/acceptor carbenes
Hansen, Stephanie R.,Spangler, Jillian E.,Hansen, Jorn H.,Davies, Huw M.L.
supporting information, p. 4626 - 4629 (2012/10/29)
Synthetically useful transformations arise from the thermal decomposition of aryldiazoacetates in the presence of primary and secondary amines without the use of a metal catalyst. Thermally generated, free donor/acceptor carbenes directly undergo N-H insertion with amines through selective aza-ylide formation to afford a variety of α-amino esters in 53-96% yields.
