139484-03-0Relevant articles and documents
Synthesis and characterization of the immobilized Ni-Zn-Fe layered double hydroxide (LDH) on silica-coated magnetite as a mesoporous and magnetically reusable catalyst for the preparation of benzylidenemalononitriles and bisdimedones (tetraketones) under
Gilanizadeh, Masumeh,Zeynizadeh, Behzad
, p. 8553 - 8566 (2018)
Herein, novel magnetic Fe3O4@SiO2@Ni-Zn-Fe layered double hydroxide (LDH) intercalated with water molecules and carbonate anions as interlayer contents was prepared as a new heterogeneous and separable nanocatalyst. The me
Preparation and study of the catalytic application in the synthesis of xanthenedione pharmaceuticals of a hybrid nano-system based on copper, zinc and iron nanoparticles
Esmaeili, Mir Saeed,Varzi, Zahra,Taheri-Ledari, Reza,Maleki, Ali
, p. 973 - 996 (2020/11/06)
A novel efficiently mixed transition metal oxides catalytic system with high catalytic activity and heterogeneity constructed of copper and zinc oxide nanoparticles is presented. For preparation of this hybrid catalytic system, carrageenan as a natural polymeric matrix has been chosen to add biocompatibility to the heterogeneous catalyst. Then, the carrageenan textures have been magnetized through the composition with iron oxide nanoparticles. Copper and zinc metallic sites are employed as the main catalytic sites for catalyzing the synthesis of xanthenedione pharmaceutical derivatives from aldehyde and dimedone. Due to the magnetic behavior of the catalyst, the purification process is carried out with high convenience. Herein, a plausible mechanism for the catalytic process is suggested and reusability of the presented catalyst is also investigated. In this report, it has been well-proven that high reaction yields are obtained for xanthenedione derivatives under mild conditions, through applying the presented hybrid catalytic system.
Selective and highly efficient synthesis of xanthenedione or tetraketone derivatives catalyzed by ZnO nanorod-decorated graphene oxide
Hasanzadeh Banakar, Sepideh,Dekamin, Mohammad G.,Yaghoubi, Amene
, p. 14246 - 14262 (2018/08/29)
ZnO nanorod-decorated graphene oxide (GO/ZnO), containing Lewis and Bronsted acid centers, was introduced as a selective, highly efficient and recoverable nanocatalyst for the pseudo three-component synthesis of diverse tetraketone or xanthenedione derivatives via condensation of aromatic aldehydes with 1,3-dicarbonyl compounds in short reaction times and good to excellent yields in H2O under refluxing and solvent-free conditions, respectively. Moreover, the GO/ZnO nanocomposite was recovered and reused at least four times without a significant decrease in its activity. Low loading of the catalyst, high to excellent yields, the elimination of any toxic heavy metals or corrosive reagents for modification of the catalyst, simple separation and purification of the products, and the reusability of the catalyst are the most significant advantages of this green protocol. The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2018.
Natural phosphate as an efficient and green catalyst for synthesis of tetraketone and xanthene derivatives
Fallah, Azadeh,Tajbakhsh, Mahmood,Vahedi, Hooshang,Bekhradnia, Ahmadreza
, p. 29 - 43 (2017/01/14)
Abstract: Natural phosphate was applied as an efficient and ecofriendly catalyst for the synthesis of tetraketones (2–2.5?h, 90–100?%) and xanthenes (6.5–8.5?h, 84–95?%) via Knoevenagel–Michael cascade reaction of aromatic aldehydes with 1,3-cyclic diketones in water and ethanol, respectively. This protocol provides several advantages over the traditional chemical synthesis, such as simple work-up, easy handling procedure, non-toxicity and stability of catalyst, low cost and environmental friendliness. Graphical Abstract: [Figure not available: see fulltext.]
Nano Fe/NaY zeolite: An efficient and reusable solid-supported catalyst for synthesis of 1-oxo-hexahydroxanthene and tetraketone derivatives
Tajbakhsh, Mahmood,Heidary, Marzieh,Hosseinzadeh, Rahman
, p. 1425 - 1439 (2016/04/26)
Nano Fe/NaY zeolite with high loading of Fe ions was successfully synthesized by the ion-exchange technique at ambient temperature. The prepared Fe/NaY was characterized by X-ray diffraction, scanning electron microscopy, energy-dispersive X-ray spectroscopy, Brunauer-Emmett-Teller (BET) surface area measurements, and Fourier-transform infrared (FT-IR) spectroscopy. The data analyses confirm the presence of iron oxide (up to 32.8 %) with average diameter of 30-40 nm on the surface of NaY zeolite. The catalytic activity of nano Fe/NaY zeolite was examined in the preparation of 1-oxo-hexahydroxanthene and tetraketone derivatives. The results showed its applicability as a green, reusable, and promising catalyst for organic synthesis. This protocol demonstrates several notable advantages including short reaction times, environmentally friendly conditions, no necessity for extraction or chromatographic purification steps, more convenient workup, high yields of products, and lack of use of any injurious solvents. The catalyst was recovered and reused up to four consecutive times without significant loss in catalytic activity. Graphical Abstract: [Figure not available: see fulltext.]
Introduction of taurine (2-aminoethanesulfonic acid) as a green bio-organic catalyst for the promotion of organic reactions under green conditions
Shirini, Farhad,Daneshvar, Nader
, p. 110190 - 110205 (2016/11/30)
Taurine (2-aminoethanesulfonic acid), a semi-essential amino acid that exists in the human body and numerous other living creatures, is used as a green bio-organic catalyst for the promotion of the Knoevenagel reaction between aldehydes and malononitrile. In the same way, tetraketones can also be produced through a Knoevenagel reaction, followed by Michael addition. 2-Amino-3-cyano-4H-pyran derivatives are simply prepared via a three-component reaction in the presence of taurine as the catalyst. All these reactions are performed in water, a green solvent. The advantages of using of taurine as the catalyst are it is environmentally friendly, low cost, commercially available, easy to separate from the reaction mixture, and has high reusability. Use of this catalyst results in acceptable reaction times, high yields and high purities of the obtained products without utilizing any organic solvents.
Silica chloride nano particle catalyzed synthesis of 2,2'-(arylmethylene) bis(5,5-dimethylcyclohexane-1,3-dione) derivatives
Karimian, Ramin,Piri, Farideh,Karimi, Babak,Moghimic, Abolghasem
experimental part, p. 111 - 115 (2012/02/01)
Silica chloride nano particle (nano SiO2-Cl), has been found to be heterogeneous catalyst for fa-cile and simple condensation of dimedone with aromatic aldehydes into 2,2′-(arylmethylene)bis(5,5-dimethylcyclohexane-1, 3-dione) derivatives in dr
Bakers' yeast catalyzed synthesis of polyhydroquinoline derivatives via an unsymmetrical Hantzsch reaction
Kumar, Atul,Maurya, Ram Awatar
, p. 3887 - 3890 (2008/02/03)
Bakers' yeast efficiently catalyzes the unsymmetrical Hantzsch reaction through a four-component coupling of aldehydes, β-ketoesters, dimedone and ammonium acetate to form polyhydroquinoline derivatives in good to excellent yields.
CHLOROSULFONATION OF 9-ARYL 3,3,6,6-TETRAMETHYLOCTAHYDROXANTHEN-1,8-DIONES
Cremlyn, Richard J.,Saunders, David
, p. 73 - 82 (2007/10/02)
The 9-aryl-3,3,6,6-tetramethyloctahydroxanthendiones (4-20) react with chlorosulfonic acid to give the sulfonyl chlorides (25, 34, 43, 53, 55, 59, 63, and 65).The xanthendione (7) from m-anisaldehyde afforded the bis-sulfonyl chloride (30).The products we
Chemistry of dimedone--Structures of aldehyde-dimedone adducts
Nagarajan, K,Shenoy, S J
, p. 73 - 87 (2007/10/02)
Novel features in the structures and stability of products of the hoary reaction of aldehydes with dimedone are described.Dimedone and cinnamaldehyde afford the bisdimedonyl derivative 3 or the perhydrochroman 5, while 4-dimethylaminocinnamaldehyde afford
