1394957-73-3 Usage
Description
(7R)-7-methyl-1,4-diazepan-5-one is a bicyclic chemical compound with the molecular formula C7H13NO. It belongs to the diazepane family and features a seven-membered ring with a nitrogen atom and a carbonyl group. The (7R) stereochemistry denotes the configuration of the chiral center in the molecule, which is crucial for its biological activity and interactions in chemical reactions. (7R)-7-methyl-1,4-diazepan-5-one serves as a potential intermediate in the synthesis of various pharmaceuticals and biologically active compounds, making it valuable in organic synthesis and medicinal chemistry research.
Uses
Used in Pharmaceutical Synthesis:
(7R)-7-methyl-1,4-diazepan-5-one is used as an intermediate in the pharmaceutical industry for the synthesis of various biologically active compounds. Its unique structure and properties allow for the creation of new drugs with potential therapeutic applications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (7R)-7-methyl-1,4-diazepan-5-one is utilized as a key compound for studying the structure-activity relationships of drug candidates. Its specific stereochemistry and reactivity contribute to the understanding of molecular interactions and the development of more effective pharmaceuticals.
Used in Organic Synthesis:
(7R)-7-methyl-1,4-diazepan-5-one is employed as a building block in organic synthesis, enabling the creation of complex molecular structures with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its versatility and unique properties make it a valuable component in the synthesis of novel compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1394957-73-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,9,5 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1394957-73:
(9*1)+(8*3)+(7*9)+(6*4)+(5*9)+(4*5)+(3*7)+(2*7)+(1*3)=223
223 % 10 = 3
So 1394957-73-3 is a valid CAS Registry Number.
1394957-73-3Relevant articles and documents
PROCESS FOR THE RESOLUTION OF (R,S)-DIAZEPANE AND DIAZEPANONE DERIVATIVES
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, (2016/04/05)
The present invention relates to a process for the preparation of an acid salt (T) of a compound of formula (A) (A) as well as to the acid salt (T) and the compound (A) as such,wherein R1 is selected from the group consisting of H, PG1 and RA, with RA being or and wherein PG1 is a suitable protecting group, and wherein n is 0 or 1, wherein the acid salt (T) is the salt of one stereoisomer of a chiral acid, preferably wherein the chiral acid salt is a tartaric acid derivative salt, preferably wherein the tartaric acid derivative salt is selected from the group consisting of 2,3-ditoluoyl tartaric acid salt, 2,3-dibenzoyl tartaric acid salt, 2,3-dianisoyl tartaric acid salt, 2,3-dibenzoyl tartaric acid mono(dimethylamide) salt and a mixture of two or more thereof. Further the present invention relates to use of (T) and/or (A) for the preparation of suvorexant.
KINETIC RESOLUTION OF CHIRAL AMINES
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Page/Page column 69; 70; 71; 72; 73, (2013/03/26)
The present invention refers to a method for the kinetic resolution of a chiral primary or secondary amine by treating the amine with a chiral, hydroxamic acid derived reagent of the formula (I). These chiral reagents are particularly useful for the kinetic resolution of cyclic amines and may be generated in situ in the presence of an N-heterocyclic carbene, thus allowing for a catalytic reaction.
