139507-52-1

Basic information

• Product Name: Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate
• Synonyms: Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate;-2-oxoacetate;Ethyl 2-(N-Methoxy-N-methylamino)
• CAS NO: 139507-52-1
• Molecular Formula: C₆H₁₁NO₄
• Molecular Weight: 161.15584
• Mol File: 139507-52-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate(139507-52-1)
• EPA Substance Registry System: Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate(139507-52-1)

Safety Data

• Hazardous Substances Data: 139507-52-1(Hazardous Substances Data)

Usage

General Description

Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate is a chemical compound with the molecular formula C6H11NO4. This chemical is a derivative of oxoacetic acid and contains an ethyl ester functional group. It also contains a methoxy and a methylamino group. Ethyl 2-(N-Methoxy-N-MethylaMino)-2-oxoacetate is commonly used as a reagent in organic synthesis, specifically in the formation of amide bonds. It has also been studied for its potential pharmacological properties, including its use in the development of pharmaceutical compounds. Additionally, it has shown promise as a building block in the synthesis of various bioactive molecules.

Upstream product

• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 4755-77-5 Ethyl oxalyl chloride 

Downstream Products

• 66644-69-7 ethyl (2-methoxyphenyl)(oxo)acetate 
• 379224-67-6 trimethylsilylethynylglyoxylic acid ethyl ester 
• 388612-66-6 Ethyl (2-fluoro-3-iodophenyl)oxoacetate 
• 1223445-72-4 ethyl 2-(5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)-2-oxoacetate 
• 1223445-73-5 2-(5-((tert-butyldiphenylsilyloxy)methyl)-4-((2R,6S)-2,6-dimethylmorpholino)-2,3-difluorophenyl)-N-methoxy-N-methyl-2-oxoacetamide 
• 1085251-02-0 ethyl 4-(4-nitrophenyl)-2-oxobut-3-ynoate 
• 1449215-58-0 ethyl 4-(cyclohex-1-en-1-yl)-2-oxobut-3-ynoate 
• 1330009-38-5 ethyl 2-oxo-4-(o-tolyl)but-3-ynoate 
• 66725-86-8 ethyl 5,5-dimethyl-2-oxohex-3-ynoate 
• 5753-96-8 ethyl 2-oxohexanoate 
• 141694-32-8 N-Methoxy-N-methyl-α-oxohexaneamide 
• 1619-73-4 ethyl 2-oxo-4-phenylbut-3-ynoate 

Relevant articles and documents

Synthesis of tetrasubstituted pyridines by the acid-catalysed Bohlmann-Rahtz reaction

New facile experimental procedures for the preparation of 2,3,4,6-tetrasubstituted pyridines in a single synthetic step have been developed. Thus, an enamino ester and alkynone react by Michael addition-cyclodehydration in a heterocyclisation process that is catalysed by acetic acid, Amberlyst 15 ion exchange resin, zinc(II) bromide or ytterbium(III) triflate. The new one-step Bronsted or Lewis acid-catalysed Bohlmann-Rahtz reaction is a simple, direct and highly expedient method for the synthesis of pyridines that proceeds at a lower reaction temperature and avoids the need to isolate reaction intermediates.

Asymmetric “Acetylenic” [3+2] Cycloaddition of Nitrones Catalyzed by Cationic Chiral PdII Lewis Acid

Highly enantioselective [3+2] cycloaddition of ynones and nitrones has been developed. Very bulky ligand, DTBM-SEGPHOS, was used for an effective asymmetric induction over distal reaction centers on the linear ynone dipolarophile and for prevention of PdII catalyst deactivation by coordination of the nitrones. The reaction has wide scope of substrates in both ynones and nitrones.

Novel pyrazinone derivatives

The present invention relates to a compound of the general formula (I): 1 [Ar1 is aryl fused to the adjacent pyrazinone ring at the 5th and 6th positions, etc., X is CO, etc., Y is CH, etc., Z is CH, etc., V is CH, etc., Wn is —(CH2)n— (n is zero to four)