1395101-38-8Relevant academic research and scientific papers
A C-N insertion of β-lactam to benzyne: Unusual formation of acridone
Kim, Jimin,Stoltz, Brian M.
, p. 4994 - 4996 (2012)
Intermolecular insertion of benzyne into the C-N bond of a β-lactam is described. This σ-insertion is followed by ring expansion that produces dihydroquinolinone, which rapidly reacts with an additional benzyne unit to afford an acridone through intramolecular C-C bond formation to the carbonyl group and rapid elimination of ethylene.
