13953-88-3

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 106-51-4 p-benzoquinone 
• 814-49-3 diethyl chlorophosphate 
• 123-31-9 hydroquinone 
• 100-46-9 benzylamine 

Downstream Products

• 80413-38-3 HOC₆H₄OP(O)(OHgOOCCH₃)2 

Relevant academic research and scientific papers

LiI/TBHP Mediated Oxidative Cross-Coupling of P(O)–H Compounds with Phenols and Various Nucleophiles: Direct Access to the Synthesis of Organophosphates

An efficient and mild method for the direct phosphorylation of phenols, alcohols, and amines with P(O)–H has been reported by LiI/TBHP mediated oxidative cross-coupling reaction. Moreover, this protocol extended to β-keto esters for the synthesis of enol phosphates using H-phosphonates. Notably, this developed method applied for the synthesis of organopesticides such as paraoxon, cyanophos, and methyl parathion. The key features of this protocol are mild conditions, short reaction time, good functional group tolerance, and broad substrate scope.

Highly selective 1,4- and 1,6-addition of P(O)-H compounds to p-quinones: A divergent method for the synthesis of C- and O-phosphoryl hydroquinone derivatives

The reaction of P(O)-H compounds with p-quinones could proceed through either 1,4- or 1,6-addition pathways by employing different additives to selectively give the corresponding C- and O-phosphoryl hydroquinone derivatives in good yields. Oxidative doubl

Ketones in the catalytic three-component "one-pot" Kabachnik - Fields synthesis of α-amino phosphonates

Reactions of carbocyclic, heterocyclic, and steroidal ketones with benzylamine and diethyl phosphite in a catalytic three-component "one-pot" synthesis of α-amino phosphonates were studied. The activities of mono-and binuclear complexes of tetra(tert-butyl)phthalocyanines as catalysts for this process were compared. Springer Science+Business Media, Inc. 2006.

A study on the selective phosphorylation and phosphinylation of hydroxyphenols

By choice of appropriate reaction conditions, the phosphorylation of hydroquinone by diethyl chlorophosphate gave predominantly the monophosphate (2). A similar reaction of phloroglucinol led to the mixture of the possible products (6, 7, and 8). The mono

Angiotensin II antagonists

This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.

Angiotensin II antagonist intermediates

This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.

Angiotensin II antagonists

This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their methods of use for antagonizing angiotensin II receptors in mammals.