139548-97-3 Usage
General Description
2,5-Difluoro-6-nitrophenol is a chemical compound with the molecular formula C6H3F2NO3. It is a pale yellow solid that is used in the synthesis of pharmaceuticals and other organic compounds. 2,5-Difluoro-6-nitrophenol is also employed as a reagent in the production of herbicides and pesticides. It is a highly reactive and toxic substance, and proper handling and storage procedures should be followed to prevent potential harm to human health and the environment. The compound is commonly used as a precursor in the synthesis of various organic compounds due to its versatile reactivity and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 139548-97-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,5,4 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 139548-97:
(8*1)+(7*3)+(6*9)+(5*5)+(4*4)+(3*8)+(2*9)+(1*7)=173
173 % 10 = 3
So 139548-97-3 is a valid CAS Registry Number.
139548-97-3Relevant articles and documents
Synthesis and Evaluation of 2-Pyridinone Derivatives as HIV-1-Specific Reverse Transcriptase Inhibitors. 2. Analogues of 3-Aminopyridin-2(1H)-one
Saari, Walfred S.,Wai, John S.,Fisher, Thorsten E.,Thomas, Craig M.,Hoffman, Jacob M.,et al.
, p. 3792 - 3802 (2007/10/02)
A series of nonnulceoside 3-aminopyridin-2(1H)-one derivatives was synthesized and evaluated for HIV-1 RT inhibitory properties.Several analogs proved to be potent and highly selective antagonists with in vitro IC50 values as low as 19 nM in the enzyme assay using rC*dG as template*primer.Two compounds from this series, 3-amino>-5-ethyl-6-methylpyridin-2(1H)-one (34, L-697,639) and the corresponding 4,7-dichloro analogue (37, L-697,661) inhibited the spread of HIV-1 IIIb infection by 95percent in MT4 cell culture at concentrations of 25-50 nM and were selected for clinical trials as antiviral agents.
