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1395895-08-5

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1395895-08-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1395895-08-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,5,8,9 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1395895-08:
(9*1)+(8*3)+(7*9)+(6*5)+(5*8)+(4*9)+(3*5)+(2*0)+(1*8)=225
225 % 10 = 5
So 1395895-08-5 is a valid CAS Registry Number.

1395895-08-5Downstream Products

1395895-08-5Relevant articles and documents

Synthesis and biological evaluation of a fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain and imaging agent

Walls, Thomas H.,Grindrod, Scott C.,Beraud, Dawn,Zhang, Li,Baheti, Aparna R.,Dakshanamurthy, Sivanesan,Patel, Manoj K.,Brown, Milton L.,MacArthur, Linda H.

, p. 5269 - 5276 (2012)

Here we report on a novel fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain with potential use as an imaging agent. Compound 2 incorporated a heptyl side chain and dansyl moiety onto the parent compound phenytoin and produced greater displacement of BTX from sodium channels and greater functional blockade with greatly reduced toxicity. Compound 2 reduced mechano-allodynia in a rat model of neuropathic pain and was visualized ex vivo in sensory neuron axons with two-photon microscopy. These results suggest a promising strategy for developing novel sodium channel inhibitors with imaging capabilities.

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