1396108-93-2Relevant academic research and scientific papers
A highly selective and naked-eye sensor for Hg2+ based on quinazoline-4(3H)-thione
Mei, Qunbo,Wang, Lingxia,Tian, Bo,Yan, Fang,Zhang, Bin,Huang, Wei,Tong, Bihai
experimental part, p. 1879 - 1883 (2012/10/08)
A highly selective colorimetric and fluorescent sensor for Hg2+, TPS (TPS = 2-(4-(diphenyl-amino)phenyl)quinazoline-4(3H)-thione), based on a 2-substituted quinazoline-4(3H)-thione derivative, was designed and characterized in this paper. TPS displays relatively strong fluorescence centered at about 468 nm. When mixing with Hg2+, TPS interacts with Hg2+ in a 2:1(TPS-Hg2+) stoichiometry via a coordination bond interaction between the sulfur atom and Hg2+ with an association constant of 4.17 × 108 M-2 (R2 = 0.96). Upon addition of Hg2+, TPS showed a remarkable decrease in fluorescence spectra (468 nm) with a clear color change from yellow to red, so TPS could serve as a naked-eye sensor for Hg2+. The sensor allow determination of Hg2+ in the working range 2.0 μM-12.0 μM with a detection limit of 1.5 μM. Upon addition of KI to the solution of TPS-Hg2+ species, the spectra can be restored to the original spectrum in both absorption and fluorescence and indicates that this sensor could be reused. The sensor exhibited excellent reproducibility, reversibility and selectivity.
