139630-39-0Relevant articles and documents
Anion Reactions of 1,3-Dithiane 1,3-Dioxide with Carbonyl Compounds: High Diastereoselectivity with Aromatic Aldehydes under Conditions of Equilibrium Control
Aggarwal, Varinder K.,Franklin, Richard,Maddock, John,Evans, Graham R.,Thomas, Abraham,et al.
, p. 2174 - 2182 (1995)
We have investigated the anion chemistry of trans-1,3-dithiane 1,3-dioxide (4) with aldehydes and ketones, and we have found that this reagent undergoes highly selective addition reactions with aromatic aldehydes but only when reactions are under equilibr
Highly stereoselective addition reactions of metallated trans-1,3-dithiane-1,3-dioxide to aldehydes
Aggarwal, Varinder K.,Franklin, Richard J.,Rice, Martin J.
, p. 7743 - 7746 (2007/10/02)
The sodium anion of trans-1,3-dithiane-1,3-dioxide reacts with unhindered aromatic and heteroaromatic aldehydes to give adducts with 95:5 to 97:3 diastereoselectivity.