1396706-81-2Relevant academic research and scientific papers
Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum
Wang, Limei,Wang, Shuqi,Yang, Shuang,Guo, Xiaojiang,Lou, Hongxiang,Ren, Dongmei
, p. 166 - 171 (2012)
Chemical examination of aerial parts of Dracocephalum heterophyllum resulted in isolation of phenolic alkaloids, including two flavonoidal alkaloids, drahebephins A and B, one imidazole alkaloid with a phenolic substituent, drahebenine, together with 15 other known compounds. Their structures were established by extensive spectroscopic data analyses. Due to the stereogenic center in the pyrrolidin-2-one ring, the flavonoidal alkaloids are chiral, although they were isolated as racemates. The enantiomers were separated by HPLC using a chiral phase and stereochemically characterized by circular dichroism (CD) spectroscopy. The structure of compound drahebenine was established by X-ray crystallography.
