1396802-70-2Relevant articles and documents
Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1receptor imaging agent
Chen, Yuan-Yuan,Wang, Xia,Zhang, Jin-Ming,Deuther-Conrad, Winnie,Zhang, Xiao-Jun,Huang, Yiyun,Li, Yan,Ye, Jia-Jun,Cui, Meng-Chao,Steinbach, J?rg,Brust, Peter,Liu, Bo-Li,Jia, Hong-Mei
, p. 5270 - 5278 (2014/12/11)
Several spirocyclic piperidine derivatives were designed and synthesized as σ1receptor ligands. In vitro competition binding assays showed that the fluoroalkoxy analogues with small substituents possessed high affinity towards σ1rece