139694-48-7

Upstream product

• 139694-39-6 (E)-3-((1S,3R,4R)-3-Isopropenyl-4-methyl-4-vinyl-cyclohexyl)-but-2-enoic acid methyl ester 
• 139694-38-5 2-((1S,3R,4R)-3-Isopropenyl-4-methyl-4-vinyl-cyclohexyl)-2-methyl-[1,3]dioxolane 
• 202194-29-4 (1R,2S,4R,5R)-2-Hydroxy-5-isopropenyl-4-methyl-4-vinyl-cyclohexanecarboxylic acid ethyl ester 
• 202194-28-3 (1R,4R,5R)-5-Isopropenyl-4-methyl-2-oxo-4-vinyl-cyclohexanecarboxylic acid ethyl ester 
• 202194-30-7 (4R,5R)-5-Isopropenyl-4-methyl-4-vinyl-cyclohex-1-enecarboxylic acid ethyl ester 
• 202194-35-2 2-((1S,4R,5R)-5-Isopropenyl-4-methyl-4-vinylcyclohex-1-yl)but-3-en-2-ol 
• 202194-37-4 (4R,5R)-5-Isopropenyl-4-methyl-4-vinylcyclohex-1-enecarboxylic acid 
• 202194-31-8 (4R,5R)-5-Isopropenyl-4-methyl-4-vinylcyclohexen-1-yl methyl ketone 
• 149404-74-0 (4R,5R)-1-Acetoxy-4-isopropenyl-5-methyl-5-vinylcyclohex-1-ene 
• 70224-50-9 (1S,3R,4R)-1-Acetyl-3-isopropenyl-4-methyl-4-vinylcyclohexane 
• 72946-10-2 diisopropyl (methoxycarbonylmethyl)phosphonate 
• 139694-47-6 (E)-3-((1S,4R,5R)-5-Isopropenyl-4-methyl-4-vinylcyclohex-1-yl)but-2-enal 

Downstream Products

• 70206-91-6 fuscol 

Relevant academic research and scientific papers

Synthetic study of marine lobane diterpenes: Efficient synthesis of (+)-fuscol

As part of a synthetic study on marine natural products, the enantioselective synthesis of (+)-fuscol 4, a representative lobane diterpene, has been achieved in 10 steps and ca. 20% overall yield from (4R,5R)-1-acetoxy-4-isopropenyl-5-methyl-5-vinylcyclohex-1-ene 3b, which itself has been prepared as a building block directed toward the asymmetric synthesis of natural products, in more than 40% overall yield from (+)-nopinone 1.

Total synthesis of marine diterpene fuscol

Marine diterpene fuscol was synthesized stereoselectively from D-mannitol via bicyclo[2.2.2]octane derivative 4, and its complete structure was established.