139706-01-7

Upstream product

• 139705-84-3 3',5'-di-O-acetyl-2'-S-(4-methoxyphenyl)-2'-thiouridine 
• 139705-87-6 3',5'-di-O-acetyl-2'-deoxy-2'(R-S)-<(4-methoxyphenyl)sulfinyl>uridine 
• 139705-88-7 3',5'-di-O-acetyl-2'-deoxy-2'(S-S)-<(4-methoxyphenyl)sulfinyl>uridine 
• 85207-45-0 2'-S-(4-methoxyphenyl)-2'-thiouridine 
• 3736-77-4 2,2'-Anhydrouridine 

Downstream Products

• 139706-06-2 3',5'-di-O-acetyl-2'-deoxy-2'(R)-fluoro-2'-<(4-methoxyphenyl)sulfonyl>uridine 
• 139706-06-2 3',5'-di-O-acetyl-2'-deoxy-2'(S)-fluoro-2'-<(4-methoxyphenyl)sulfonyl>uridine 
• 139706-14-2 2'-deoxy-2'(S)-fluoro-2'-<(4-methoxyphenyl)sulfonyl>cytidine 
• 139706-10-8 2'-deoxy-2'(S)-fluoro-2'-<(4-methoxyphenyl)sulfonyl>uridine 
• 139706-12-0 1-<3,5-di-O-acetyl-2-deoxy-2(S)-fluoro-2-<(4-methoxyphenyl)sulfonyl>-β-D-erythro-pentofuranosyl>-4-(1,2,4-triazol-1-yl)pyrimidin-2-one 

Relevant academic research and scientific papers

Fluorination at C2', C3' and C5' of nucleosides with 1-chloromethyl-4-fluoro-1,4-diazabicyclo[2.2.2]octane bis(tetrafluoroborate) SELECTFLUOR(TM) reagent

Electrophilic fluorination of thioaryl ethers on the sugar component of nucleosides with commercially available SELECTFLUOR(TM) reagent provides a new method for the synthesis of C2', C3' and C5' fluoronucleosides.

Nucleic Acid Related Compounds. 73. Fluorination of Uridine 2'-Thioethers with Xenon Difluoride or (Diethylamino)sulfur Trifluoride. Synthesis of Stable 2'--2'-deoxy-2'-fluorouridines

Treatment of 2,2'-anhydro-1-β-D-arabinofuranosyluracil with thiolate anions gave the 2'-S-alkyl(and aryl)-2'-thiouridines (1).Oxidation of 3',5'-di-O-acetyl-2'-S-alkyl(and aryl)-2'-thiouridines (2) with 3-chloroperoxybenzoic acid (MCPBA) gave the diastere