139715-33-6Relevant articles and documents
3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: Potential candidates for chemoprevention
Nagle, Amrita A.,Reddy, Shridhivya A.,Bertrand, Helene,Tajima, Hisashi,Dang, Truong-Minh,Wong, Siew-Cheng,Hayes, John D.,Wells, Geoffrey,Chew, Eng-Hui
supporting information, p. 1763 - 1774 (2014/08/18)
Induction of cytoprotective phase 2 enzymes through inhibition of Keap1, a repressor of transcription factor Nrf2, is a cancer-prevention strategy. Compounds that elicit antiinflammatory and cytoprotective effects are promising candidates for chemoprevent