139719-91-8Relevant academic research and scientific papers
Synthesis of substituted azulenes via Pt(II)-Catalyzed ring-expanding cycloisomerization
Usui, Kazuteru,Tanoue, Kensuke,Yamamoto, Kosuke,Shimizu, Takashi,Suemune, Hiroshi
, p. 4662 - 4665 (2014)
Substituted azulenes, valuable structures for electronic devices and pharmaceuticals, have been synthesized by the platinum(II)-catalyzed intramolecular ring-expanding cycloisomerization of 1-en-3-yne with ortho-disubstituted benzene. This novel method provides an alternative route for the efficient synthesis of substituted azulenes. The reaction mechanism of selected catalytic transformations was explored using density functional calculations.
Vaulted biaryls in catalysis: A structure-activity relationship guided tour of the immanent domain of the VANOL ligand
Guan, Yong,Ding, Zhensheng,Wulff, William D.
supporting information, p. 15565 - 15571 (2013/11/19)
The active site in the BOROX catalyst is a chiral polyborate anion (boroxinate) that is assembled in situ from three equivalents of B(OPh) 3 and one of the VANOL ligand by a molecule of substrate. The substrates are bound to the boroxinate by Hbonds to oxygen atoms O1-O3. The effects of introducing substituents at each position of the naphthalene core of the VANOL ligand are systematically investigated in an aziridination reaction. Substituents in the 4,4′- and 8,8′-positions have a negative effect on catalyst performance, whereas, substituents in the 7- and 7′-positions have the biggest impact in a positive direction. VANOL destination: The active site in the BOROX catalyst is a chiral polyborate anion (boroxinate; see figure) that is assembled in situ from three equivalents of B(OPh)3 and one of the VANOL ligand by a molecule of substrate. The effects of introducing substituents at each position of the naphthalene core of the VANOL ligand are systematically investigated in an aziridination reaction. Copyright
Novel 3-aminochromans as potential pharmacological tools for the serotonin 5-HT7 receptor
Holmberg, Paer,Tedenborg, Lars,Rosqvist, Susanne,Johansson, Anette M.
, p. 747 - 750 (2007/10/03)
The synthesis of novel C6-aryl substituted derivatives of 3-(dimethylamino)chroman is described. The novel derivatives display 5-HT 7 receptor affinities that varies from nM to μM, indicating that this small set of derivatives constitute a nove
Concave reagents+. New 2′-substituted m-terphenyls
Abbass, Michael,Kuehl, Christine,Manthey, Christian,Mueller, Anja,Luening, Ulrich
, p. 1325 - 1344 (2007/10/03)
New 2′-substituted 2,2″,6,6″-tetramethyl-1,1′: 3′,1″-terphenyls have been synthesized. Solubility of concave acids 4b-6b could be enhanced by substitution in 4 and 4″ position, allowing the study of hydrogen-bonded heterodimers. Concave acids show larger
