1397226-71-9

Upstream product

• 181514-22-7 methyl 4-(2-(2,2,2-trifluoroacetamido)ethyl)benzoate 
• 91-47-4 2,3-diphenylacrylic acid 
• 220247-50-7 methyl 1,2,3,4-tetrahydroisoquinoline-7-carboxylate 

Downstream Products

• 1397227-01-8 2-(2,3-diphenylacryloyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid 
• 1397218-25-5 2-(2,3-diphenylacryloyl)-N-hydroxy-1,2,3,4-tetrahydroisoquinoline-7-carboxamide 

Relevant academic research and scientific papers

HISTONE DEACETYLASE INHIBITORS

Provided herein are isoform selective histone deacetylase inhibitors of the formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, metabolites, prodrugs, solvates, pharmaceutically acceptable salts and compositions thereof. These compounds are isoform selective inhibitors of HDACs and are useful as a therapeutic or ameliorating agent for diseases that are involved in cellular growth such as cancer, malignant tumors, autoimmune diseases, skin diseases, fungal infections, protozoal infections, HIV, inflammation and CNS disorders.